CrossRef citations to date
Major Article

Adverse childhood experiences, risk of opioid misuse and its pathway among students at a public university

, MSW/MPH, , PhD, MS, MPA, , MS, , BS & , PhD, MPH
Received 21 Dec 2020
Accepted 29 Oct 2021
Published online: 17 Nov 2021


Objective: We examine role of ACEs and pathways to risk of opioid misuse among young adults. Participants and Methods: A cross-sectional survey of validated measures of ACEs, risk of opioid misuse, and health conditions with a sample of 1,402 students from a large public university followed by multivariate logistic regression and pathway analysis. Results: Majority (61%) of participants reported at least one ACE. A dose-response relationship between numbers of ACEs with risk for opioid misuse was present. Compared to participants with no ACEs, participants with ≥4 ACEs and 0–3 ACEs were 2.93 (95% CI: 1.95, 4.39; p < 0.001) and 1.96 (95% CI: 1.46, 2.65; p < 0.001) times more likely to be at risk for opioid misuse, respectively. Having at least one existing or past health condition significantly mediated the association. Conclusions: Our findings suggest need to include assessment of ACEs as a screening criterion for opioid prescription and administration among college-aged individuals.


No funding was used to support this research and/or the preparation of the manuscript.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 45.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 102.00 Add to cart

Purchase access via tokens

  • Choose from packages of 10, 20, and 30 tokens
  • Can use on articles across multiple libraries & subject collections
  • Article PDFs can be downloaded & printed
From USD 450.00
per package
Learn more
* Local tax will be added as applicable

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.